Please use this identifier to cite or link to this item: http://cimav.repositorioinstitucional.mx/jspui/handle/1004/991
Porous Biodegradable Polyurethane Scaffolds Prepared by Thermally Induced Phase Separation
ALBERTO MARTINEZ VILLAFAÑE
JOSE ALBERTO DUARTE MOLLER
Acceso Abierto
Sin Derechos Reservados
Polyurethane
Guide regeneration techniques have been recently used to heal soft and hard tissue defects. In this approach, scaffolding plays an important role. Hydroxypatite (HA) resembles the natural bone mineral and has shown good bone bonding properties. In this work, porous polyurethanes have been prepared by a thermally induced phase separation technique. Freeze drying of the separated polymer/solvent phase produced foams with co-continuous structure of interconnected pores. The microstructure can be controlled by varying polymer concentration, quenching temperature, and co-solvent utilized. This homogenizing technique can lead to the preparation of porous materials with controllable and reproducible morphology. SEM analysis showed that the pore size range varied from a few microns to a few hundred microns. Due to the interconnected pores, and their biocompatibility and bioactivity; they are promising scaffolds for bone – tissue engineering.
2006
Artículo
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